How Much Klonopin for Anxiety, Panic Disorder, Seizures and infants Dosage Calculators.
1. Panic Disorder
- Initial Dosage: The recommended starting dosage for adults is 0.25 mg taken twice daily. This allows the body to adjust to the medication and helps assess its effectiveness.
- Titration: After three days, the dosage may be increased to 0.5 mg twice daily if needed.
- Maximum Dosage: The maximum recommended dose for panic disorder is 4 mg per day, typically divided into two doses of 2 mg each.
- Clinical Trials Results: In clinical studies, at a dose of 1 mg/day, 74% of patients were free from full panic attacks compared to 56% in the placebo group. Higher doses (2-4 mg/day) were less effective and associated with more side effects.
2. Seizure Disorders
- Initial Dosage: For adults, the initial recommended dosage is 0.5 mg taken three times per day, with a maximum initial dose of 1.5 mg/day divided into three doses.
- Titration: Dosage may be increased in increments of 0.5 to 1 mg every three days until seizures are adequately controlled or side effects occur.
- Maximum Dosage: The maximum daily dose for seizure disorders can reach up to 20 mg, divided into multiple doses throughout the day.
3. Pediatric Dosage
- For children under 10 years or weighing less than 30 kg, the starting dose is between 0.01 and 0.03 mg/kg/day, not exceeding 0.05 mg/kg/day, divided into two or three doses.
- The maintenance dosage should be between 0.1 to 0.2 mg/kg/day.
[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/017533s061lbl.pdf
[2] https://www.medicalnewstoday.com/articles/drugs-klonopin-dosage
[3] https://www.drugs.com/dosage/klonopin.html
[4] https://www.rxlist.com/klonopin-drug.htm
[5] https://www.ncbi.nlm.nih.gov/books/NBK556010/
[6] https://www.mayoclinic.org/drugs-supplements/clonazepam-oral-route/proper-use/drg-20072102
[7] https://reference.medscape.com/drug/klonopin-clonazepam-342900
[8] https://www.sciencedirect.com/topics/chemistry/clonazepam